Patents and Publications
Sixteen granted US patents and one filed, fifteen-plus peer-reviewed publications with 500+ citations, and conference presentations across IEEE MEMS, IEEE Transducers, MicroTAS, the Solid-State Sensor and Actuator Workshop at Hilton Head, the Gordon Research Conference on Biointerface Science, and OFC. The work spans silicon photonics, surface engineering, microfabrication, and mechanical design.
Granted Patents
Evanostics: Silicon Photonics and Optical Sensing
- US 9,976,192: Waveguide-Based Detection System with Scanning Light Source (2018)
- US 10,018,566: Partially Encapsulated Waveguide-Based Sensing Chips (2018)
- US 10,590,493: Waveguide-Based Detection System with Scanning Light Source (2020, continuation)
- US 10,660,619: Cartridges for Oral Fluid Analysis and Methods of Use (2020)
- US 11,262,367: Optical Reader for Analyte Testing (2022)
- US 11,940,454: Optical Reader for Analyte Testing (2024, continuation)
- US 12,066,383: Optical Analyte Detection (2024)
- US 12,429,490: Optical Reader for Analyte Testing (2025, continuation)
Corium MicroCor: Process Engineering and Microfabrication
- US 9,962,534: Microarray for Delivery of Therapeutic Agent (2018)
- US 10,857,093: Microarray for Delivery, Vacuum Fill Method (2020)
- US 11,052,231: Microarray for Delivery, Detachable Distal Area (2021)
University of Washington: Surface Engineering
- US 7,442,515: Apparatus and Methods for Binding Molecules and Cells (2008)
- US 8,142,168: Vibration-Driven Droplet Transport on Textured Surfaces (2012)
Corium MicroCor Applicator: Mechanical Design
- US 10,195,409: Multiple Impact Microprojection Applicators (2019)
- US 10,245,422: Microprojection Applicators and Methods of Use (2019)
- US 11,110,259: Microprojection Applicators (2021)
Filed (Pending)
- Water Immersion Optical System (Illumina)
Selected Peer-Reviewed Publications
- Shastry, A., Case, M.J., Böhringer, K.F. Directing Droplets Using Microstructured Surfaces. Langmuir 22(14): 6161 (2006). 400+ citations.
- Seriburi, P., Shastry, A., Ren, T., Gales, S., Böhringer, K.F., Meldrum, D.R. Measurement of the Cell-Substrate Separation and the Projected Area of an Individual Adherent Cell Using Electric Cell-Substrate Impedance Sensing. Analytical Chemistry 80(10): 3677–3683 (2008).
- Duncombe, T.A.†, Erdem, E.Y.†, Shastry, A.†, Baskaran, R., Böhringer, K.F. Controlling Liquid Drops with Texture Ratchets. Advanced Materials 24(11): 1545 (2012). Cover article. †Equal first-author contribution (alphabetical by last name); follows Shastry’s 2007 originating disclosure at Transducers and US 8,142,168.
Selected Conference Presentations
Podium Talks
- Shastry, A., Lal, R. ChipCE: A Silicon Microsystem for Migration, Separation and Detection of DNA. 17th IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS 2003), Kyoto, Japan.
- Shastry, A., Case, M.J., Böhringer, K.F. Engineering Surface Texture to Manipulate Droplets in Microfluidic Systems. 18th IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS 2005), Miami Beach, FL.
- Shastry, A., Case, M.J., Böhringer, K.F. Directing Droplets Using Microstructured Surfaces. Technical Digest of the 12th Solid-State Sensor, Actuator and Microsystems Workshop, Hilton Head Island, SC, June 4–8, 2006.
- Shastry, A. Gordon Research Conference on Biointerface Science, October 22–27, 2006, Old Saybrook, CT. 1-hour talk.
- Shastry, A. et al. Selective High Efficiency In-Flow Single Cell Electroporation. 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS 2006), Tokyo, Japan.
- Shastry, A., Taylor, A.D., Böhringer, K.F. Micro-Structured Surface Ratchets for Droplet Transport. 14th International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2007), Lyon, France.
- Shastry, A. Session presentation on silicon-photonics evanescent-field biosensing, Optical Fiber Communications Conference (OFC), Anaheim, CA, March 2016.
- Shastry, A. From Ideas to Launch: Multidisciplinary Medical Product Development. Tau Beta Pi (UC Santa Cruz chapter), November 2019.
- Shastry, A. The Evanostics Story: A Step Towards Saving Lives from Drug Overdose. Bio2Device Group, Bay Area, February 8, 2021.
- Shastry, A. Converting Research into Products: Insights from My Multidisciplinary Problem-Solving Journey. TechEx, India, June 23, 2022.
Co-Authored Peer-Reviewed Conference Papers
- Sarkar, A., Mitra, B., Shastry, A., Wadia, S., Mulherkar, R., Lal, R. A Low Voltage Single Cell Electroporator with a Microfabricated Sense-Porate Aperture. IEEE MEMS 2004, Maastricht, Netherlands. Poster.
- Two additional co-authored μTAS 2006 (Tokyo) papers on surface-wetting physics: hydrophobic non-fouling surfaces; bounds on contact angle hysteresis.