Ashutosh Shastry

Taking Technology Platforms
from Concept to Pilot Line · Lab to Fab

Engineering leader, hardware platforms. Twenty years across microfabrication and sensing systems, eight in silicon photonics. Two platforms taken from first principles to clinical-stage validation

The work runs across wearable form factors, including patch pumps, dissolving microneedles, and silicon-photonics biosensors, and the integration discipline that makes them ship. That discipline now applies at nEye Systems, taking MEMS-based silicon-photonic optical circuit switches from lab to fab for AI data centers.

Technology journey
Evanostics: Silicon-Photonics Biosensor Program from Concept to Clinical Stage

I led the engineering across the workstreams that had to converge (photonics and chip fabrication, biomolecule printing and multiplex assay development, modular fluidics, and a clinical-grade reader) for a saliva-based diagnostic that reached clinical validation. The program got there because we built a common language for naming and resourcing the interface problems between disciplines.

13K+ cartridges produced
95% final-batch yield
8 patents granted
2 clinical studies
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Recent article
Non-Invasive Glucose Sensing: A First-Principles Architecture

Why this problem has taken a decade of serious industrial effort, what the binding constraints actually are, and why integration across disciplines (not depth in any single one) is what the work really requires.

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About
Integration across disciplines is the through-line of my work

Career across silicon photonics biosensors, DNA sequencing platforms, dissolvable microneedle drug delivery, and precision optical spectroscopy. Sixteen patents, more than fifteen peer-reviewed publications cited 500+ times. Edison Silver Medal, Game Changer in Medical Technology (2010) for the Corium MicroJet needle-free injector.

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Video thumbnail
The oral-fluid cartridge in the reader. Watch on YouTube.

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