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Ashutosh Shastry

Taking Technology Platforms from Concept to Pilot Line

Twenty years across silicon photonics, sensing systems, and microfabrication, guided by systems thinking and first principles

Physics to Product

Wearable form factors, including patch pumps, dissolving microneedles, and silicon-photonics biosensors

About
Integration across disciplines is the through-line of my work

Twenty years across silicon photonics biosensors, DNA sequencing platforms, dissolvable microneedle drug delivery, and precision optical spectroscopy. Sixteen patents, more than fifteen peer-reviewed publications cited 500+ times. Edison Silver Medal, Game Changer in Medical Technology (2010) for the Corium MicroJet needle-free injector.

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Recent article
Non-Invasive Glucose Sensing: A First-Principles Architecture

Why this problem has taken a decade of serious industrial effort, what the binding constraints actually are, and why integration across disciplines (not depth in any single one) is what the work really requires.

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Technology journey
Evanostics: Silicon-Photonics Biosensor Program from Concept to Clinical Stage

I led the engineering across the workstreams that had to converge (photonics and chip fabrication, biomolecule printing and multiplex assay development, modular fluidics, and a clinical-grade reader) for a saliva-based diagnostic that reached clinical validation. The program got there because we built a common language for naming and resourcing the interface problems between disciplines.

13K+ cartridges produced
95% final-batch yield
8 patents granted
2 clinical studies
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Video thumbnail
The Evanostics oral-fluid cartridge in the reader. Watch on YouTube.